BioHale® Sucrose LE is a non-reducing sugar designed to support reliable process performance and product stability across the biopharmaceutical manufacturing workflow. Its multifunctional properties make it a valuable ingredient for applications ranging from up-and downstream processing.

Designed to Support Upstream and Downstream Success

As a multifunctional excipient, BioHale® Sucrose LE delivers value across the bioprocess workflow.

In upstream bioprocessing, BioHale® Sucrose LE provides a carbohydrate source to support robust culture performance and process efficiency. Its readily utilizable carbon and energy contribution makes it particularly relevant to microbial fermentation and other biomanufacturing applications where controlled nutrient inputs are critical to reproducible process performance. Beyond its nutritional function, sucrose can also contribute to cellular preservation by helping cells withstand processing-related stresses. This makes BioHale® Sucrose LE a versatile option for processes where both culture performance and cellular integrity are important considerations.

In downstream processing and formulation, BioHale® Sucrose LE functions as an effective stabilizing agent for proteins and other sensitive biomolecules. It can help preserve native protein structure and reduce aggregation during processing and storage. These stabilizing properties are particularly relevant during processing and product handling, including freezing, and lyophilization. By supporting the structural integrity of sensitive biomolecules, BioHale® Sucrose LE can help maintain product quality throughout these critical stages.