Continuous Manufacturing is reshaping pharmaceutical development and production. However, successful implementation depends on material performance, process understanding, and informed decision-making across the entire product lifecycle.

DFE Pharma’s Continuous Manufacturing platform brings together CM-ready excipients, access to flexible testing environment, and applied scientific expertise to support confident, data-driven CM development and optimization.

Why Continuous Manufacturing requires a platform approach.

 While Continuous Manufacturing offers advantages in efficiency, speed, and robustness, adoption and optimization often raise questions around:

• Material behaviour under continuous processing
• Practical evaluation without disrupting commercial operations
• Translating data into confident next steps

DFE Pharma addresses these challenges through a platform approach that integrates excipients, process understanding, and expertise  enabling customers to move forward with clarity.

The DFE Pharma Continuous Manufacturing platform

 DFE Pharma supports pharmaceutical manufacturers across different stages of CM maturity from early exploration to optimization and lifecycle management.

This is achieved through three complementary pillars:

Excipients

Achieve robust CM formulations with excipients designed for process stability and simplified processing.

DFE Pharma offers a differentiated excipient portfolio developed and characterized to support continuous manufacturing processes.

• CM-ready excipients to support stable and reproducible processing
• High and controlled product consistency to support robust lifecycle management
• Functional excipients enabling simplified formulations and system design
• Quality attributes aligned with impurity control and regulatory expectations
• Responsibly produced excipients supporting sustainability objectives

 Equipment

Learn, test, and validate CM concepts in a safe, flexible, and representative environment.

DFE Pharma enables access to representative, non-GMP Continuous Manufacturing evaluation environment as a part of the CM-platform.

• Practical evaluation without customer investment in infrastructure
• No impact on existing GMP production lines
• Representative end-to-end CM process assessment
• Integrated analytical support to generate decision-relevant insights
• Structured evaluations designed to support translation and decision-making

Expertise

Turn CM science into confident, data-driven decisions.

The CM platform is supported by multidisciplinary expertise spanning formulation development, process understanding, analytics, and variability science.

• Expertise grounded in practical CM experience
• Active contribution to scientific and industry discussions on CM
• Expert guidance supporting formulation development and process optimization
• Training and knowledge-sharing programs to support capability building
• Advanced approaches to support variability understanding and regulatory alignment