Pharmacel® 112

Baixo teor de umidade (LOD < 1,5% p/p)

Adequado para IFAs altamente sensíveis à umidade

Embalagem altamente protetora

Dose Sólida Oral

Informação do produto

Pharmacel® 112 é um grau de celulose microcristalina diretamente compressível com baixo teor de umidade (LOD < 1,5% p/p), especialmente projetado para a formulação de ingredientes farmacêuticos ativos (IFAs) com alta sensibilidade à umidade.

Pharmacel® 112 pode ser usado em uma ampla gama de formas de doses orais sólidas (DOS) como ligante, agente de compressão, diluente e/ou auxiliar de desintegração. Seu baixo teor de umidade pode levar à melhora da estabilidade do fármaco sem comprometer o desempenho do produto final.

A embalagem altamente protetora garante a proteção completa do Pharmacel® 112 contra a absorção de umidade ao longo dos 4 anos de prazo de validade

Embalagem

- Saco de papel multicamada de 25 kg com forro em PE

- Tamanho da amostra: 500g

Local de produção

Cuddalore, India

Tipos de Produto: Celulose microcristalina
Funcionalidade: Enchimento-aglutinante, Diluente, Fichário, Desintegrante
Processo recomendado: Compressão direta, Mistura seco
Formas farmacêuticas: Comprimidos, Cápsula (Dose Oral Sólida), Comprimido de desintegração oral

Dados típicos do produto

X10: 40
X50: 90
X90: 180

Densidade aparente (g/L)

Densidade aparente (g/L): 330

Hausner ratio (-)

Hausner ratio (-): 1.39

LOD (% w/w)

LOD (% w/w): 1,3

Documentação

ALBA Pharmacel
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Oral Solid Dose Brochure Ver
Declaração de contaminantes de Pharmacel
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Declaração alimentar Celulose Microcristalina
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Informação Nutricional Pharmacel
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Especificação de produto Pharmacel 112
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DFE Pharma Leaflet Pharmacel 112 Ver

Fluxograma de processo Pharmacel® 112
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Stability Summary Pharmacel®112
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Re-compaction properties of lactose and mcc Ver
Roller compaction of anhydrous lactose and mcc Ver
MCC Effect of Increasing Pharmacel Concentration on the Tableting Properties of DC Diluents Ver
Impact of excipient and blend properties on feeding consistency for continuous manufacturing Ver
Choosing the optimal lactose and MCC grade for formulating moisture sensitive drugs Ver

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