出版物

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我们坚信,正是通过众多出版物,研究——包括其理论贡献和实践贡献——才能传播给其他人。这能为我们领域的其他研究人员提供新数据,同时有助于推进整个行业的知识更新及其应用。

我们的DFE Pharma专家定期在我们的领域发表科学文章,以推动创新并传播知识。他们还经常在科学(行业)活动中担任发言人。

请查找如下文所示的最新文章:

通用

Water activity and moisture: the complexity and interrelationships explained
期刊:Tablets & Capsules (2020)
链接: https://www.e-digitaleditions.com/i/1287521-tc0920/29?
作者: P.H.M. Janssen, R.J. Blezard, B.H.J. Dickhoff (DFE Pharma)

Chapter 5 - Application of lactose in the pharmaceutical industry
图书: Lactose: Evolutionary Role, Health Effects and Applications (2019)
链接: https://www.sciencedirect.com/science/article/pii/B9780128117200000052
作者: Gerald A. Hebbink, Bastiaan H.J. Dickhoff (DFE Pharma)

The flowability of lactose powders to optimize tableting processes
期刊: On drug Delivery (2020)
链接: https://ondrugdelivery.com/the-flowability-of-lactose-powders-to-optimise-tableting-processes/
作者: Aurélien Neveu, Geoffrey Lumay (GranuTools), Pauline Janssen (DFE Pharma)

Impact of Powder Properties on the Rheological Behavior of Excipients
期刊: Pharmaceutics MDPI (2021)
作者: Pauline H. M. Janssen, Bastiaan H. J. Dickhoff (DFE Pharma), Sébastien Depaifve, Aurélien Neveu, Filip Francqui (GranuTools)

The effect of excipient particle size on the reduction of compactibility after roller compaction
Journal: International Journal of Pharmaceutics: X (2022)
Link: https://www.sciencedirect.com/science/article/pii/S2590156722000068
Authors: Pauline H. M. Janssen, Maarten Jaspers, Timo P. Roelofs, Bastiaan H. J. Dickhoff (DFE Pharma), Robin Meier (Bohle)

质量标准和数据

Technical insight into potential functional-related characteristics (FRCs) of sodium starch glycolate, croscarmellose sodium and crospovidone.
期刊: Drug Delivery Science and Technology (2022)
链接: https://www.sciencedirect.com/science/article/pii/S177322472200171X
作者: Alberto Berardi, Pauline Janssen, Bastiaan H.J. Dickhoff (DFE Pharma)

Science and risk-based specification setting for excipients
期刊: European Pharmaceutical Review (2020)
链接: https://www.europeanpharmaceuticalreview.com/article/130244/european-pharmaceutical-review-issue-5-2020/ 
作者: B.H.J. Dickhoff, Sunil Kumar Nataraj (DFE Pharma), Kalyan Janjanam (Epic Pharma)

Eye on Excipients: Using multivariate analysis to de-risk the use of excipients
期刊: Tablets & Capsules (2021)
链接: https://www.e-digitaleditions.com/i/1331851-tc0121/47?
作者: P.H.M. Janssen, B.H.J. Dickhoff (DFE Pharma)

Quality by design: Using multivariate analysis of batch-to-batch excipient variation to reduce risk
期刊: Tablets & Capsules (2019)
链接: https://www.e-digitaleditions.com/i/1173734-tc1019/41
作者: B.H.J. Dickhoff, T. Schigt, H.L. Blaauw, A.W. van Gessel (DFE Pharma)

连续生产

Understanding and Accounting for Excipient Variability in Continuous Tablet Manufacturing (CM)
链接: PDF Whitepaper DFE_CM.pdf (2021)
作者: Mara van Haandel (DFE Pharma)

Impact of excipients on batch and continuous powder blending
期刊: Powder Technology (2021)
链接: https://www.sciencedirect.com/science/article/pii/S0032591021001170?via%3Dihub
作者: Maarten Jaspers, Myrthe T.W. de Wit, Sri Sharath Kulkarni, Pauline H.M. Janssen, Mara M.W. van Haandel, Bastiaan H.J. Dickhoff (DFE Pharma), Bernhard Meir (Gericke) 

Batch versus continuous blending of binary and ternary pharmaceutical powder mixtures
期刊: International Journal of Pharmaceutics (2022)
链接: https://www.sciencedirect.com/science/article/pii/S2590156721000402
作者: Maarten Jaspers, Sri Sharath Kulkarni, Timo P. Roelofs, Myrthe T.W. de Wit, Pauline H.M. Janssen, Bastiaan H.J. Dickhoff (DFE Pharma), Florian Tegel, Ralf Weinekötter (Gericke)

吸入剂

Inhalation powder: The result of the magic triangle of excipients, blending and filling processes
期刊: Techno Pharm (2021)
链接: https://www.ecv.de/beitrag/TechnoPharm/Inhalation_powder
作者: Dr. Olukayode I. Imolle (Hosokawa Micron), Mohit Mehta and Harry Peters (DFE Pharma), Marc Zerrer and Dr. Elke Sternberger-Rützel (Harro Höfliger)

3D打印

Bringing a whole new dimension to lactose
链接: https://dfepharma.com/-/media/Project/DFE/Corporate/Bringing-a-whole-new-dimension-to-lactose.pdf
作者: Korinde A. van den Heuvel-Jansen, Cas J. Wiebinga (DFE Pharma)

Evaluation of lactose-based 3D powder bed printed pharmaceutical drug product tablets
期刊: Powder Technology (2021)
链接: https://www.sciencedirect.com/science/article/pii/S0032591021004575
作者: Korinde A. van den Heuvel-Jansen, Myrthe T.W. de Wit, Bastiaan H.J. Dickhoff (DFE Pharma)

生物制品

The importance of disaccharide excipients in biologics
期刊: European Pharmaceutical Review (2021)
链接: https://www.europeanpharmaceuticalreview.com/article/143124/the-importance-of-disaccharide-excipients-in-biologics/
作者: B.H.J. Dickhoff, Sunil Kumar Nataraj (DFE Pharma), Thontesh GC (Apotex Pharmaceuticals)