Pharmacel® sMCC 90

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Pharmacel® sMCC 90是一种硅化微晶纤维素，为具有挑战性的口服固体制剂提供协同解决方案。将微晶纤维素与二氧化硅共加工后可增加其表面积，从而提高粉末流动性，获得更优异的可压性，使设计的处方更为稳健。

Pharmacel® sMCC 90的优点

作为对我们现有成熟辅料系列产品的补充，研发该新品旨在为全球客户提供最高品质的辅料和服务。与传统辅料相比，Pharmacel® sMCC 90具有以下优点：

- 改善压片特性

- 提高生产速度

- 加速处方开发

改善压片特性

Pharmacel® sMCC 90是一种用于直接压片工艺的高性能辅料。与传统辅料相比，应用Pharmacel® sMCC 90可在较高的压片速度下仍实现较低的顶裂率，可使片剂硬度增加20%

提高生产速度

片剂的生产速度取决于几个中间步骤的速度。Pharmacel® sMCC 90可提高多个单元操作的加工速度。此外，Pharmacel® sMCC 90可使物料快速且更均一地从料斗中流出。

Pharmacel® sMCC 90的优良流动性可确保片重一致性，250 mg安慰剂片的片重差异低于1%。

加速处方开发

与传统辅料相比，Pharmacel® sMCC 90正是由于改善了流动性和可压性，从而缓解处方带来的诸多挑战。此外，较低的润滑剂和驻留时间敏感性更易于工艺放大。此外，与常规级产品相比，Pharmacel® sMCC 90可减少使用的辅料数量，不再需要加入二氧化硅的步骤。

包装

- 25 kg多层纸袋（PE内衬袋)

- 样品量：500 g

产地

印度Nagpur

有效期

48个月

: 微晶纤维素
辅料功能: 粘合剂, 稀释剂, 填充剂-粘合剂, 崩解剂
推荐工艺: 直接压片, 干混, 湿法制粒
剂型: 胶囊剂（口服固体制剂）, 口腔崩解片, 片剂, 颗粒剂

典型产品数据

粒度分布（μm）

X10: 35
X50: 110
X90: 270

堆密度（g/L）

堆密度（g/L）: 318

豪斯纳比(-)

豪斯纳比(-): 1.46

干燥失重LOD (% w/w)

干燥失重LOD (% w/w): 4.4

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The PDFs are technically modified by DFE Pharma’s controlled documentation system. Please follow the instructions to download and save our documents:
1. Click on "Download document"
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3. This will open a new browser window with an empty document. Click on "Save". The document will be saved to your computer.
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Please follow the instructions to see our documents:
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2. The document will be displayed in your web browser. If a login window to MasterControl appears, please use an incognito/private window, or clear the cache of your browser.
Save documents

The PDFs are technically modified by DFE Pharma’s controlled documentation system. Please follow the instructions to download and save our documents:
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2. The document will open in Master Control, in a window of your browser. Click on Download>PDF
3. This will open a new browser window with an empty document. Click on "Save". The document will be saved to your computer.
4. This will open a new browser window with an empty document. Click on "Save". The document will be saved to your computer.
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效期声明
IMPORTANT: PLEASE READ BEFORE VIEWING OR SAVING DOCUMENTS
View documents

Please follow the instructions to see our documents:
1. Click on "Download document"
2. The document will be displayed in your web browser. If a login window to MasterControl appears, please use an incognito/private window, or clear the cache of your browser.
Save documents

The PDFs are technically modified by DFE Pharma’s controlled documentation system. Please follow the instructions to download and save our documents:
1. Click on "Download document"
2. The document will open in Master Control, in a window of your browser. Click on Download>PDF
3. This will open a new browser window with an empty document. Click on "Save". The document will be saved to your computer.
4. This will open a new browser window with an empty document. Click on "Save". The document will be saved to your computer.
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Re-compaction properties of lactose and mcc 查看
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