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Lactohale® 210

细乳糖

不规则形状颗粒研磨乳糖

优化处方流动性和性能的理想辅料

吸入制剂

Lactohale®吸入混合产品是一系列经过严格选择的产品，是助您获得最佳粒度分布的理想产品。吸入级乳糖的特性通常基于不同的参数进行选择，如储药装置中所需的流动性、填充平台所需的流动性和所需的药物沉积率。我们可提供非常全面的标准规格的Lactohale®，以满足客户的多样化需求。

DFE Pharma还通过一系列的吸入乳糖混合产品为客户提供支持。Lactohale® 206、Lactohale® 210、Lactohale® 220、Lactohale® 230和Lactohale® 300之Lactohale®产品系列特别适用于处于早期开发阶段的处方设计师或希望探索其处方设计空间的处方设计师使用。

Laser Diffraction Particle Size Graph Lactohale 210

干粉吸入剂的质量源于设计方法

Lactohale® 206是粗磨一水α-乳糖，已去除了细乳糖颗粒。在需要优良流动性的应用中，粗磨乳糖可用作基础乳糖。将该粗品与细乳糖混合，为处方设计师提供了一种优化干粉吸入混料流动性和沉积率的方法。这种优化可以使用不同类型的细颗粒，即Lactohale® 210、Lactohale® 220、Lactohale® 230和Lactohale® 300。与极细乳糖混合通常对药物沉积率有显著影响。添加略粗的细颗粒，如Lactohale® 210，主要对粉末粘附性有影响，而对沉积率的影响有限。

DFE Pharma可提供各种粒度规格的研磨和筛分吸入乳糖，商品名为Lactohale®和Respitose®。客户通常使用Lactohale® DoE系列产品开始其处方开发，然后可以转变为定制，以微调其处方的性能。通过密切合作，可以完美匹配流动性与适宜的细颗粒含量，确保最佳的产品性能。定制的Lactohale®及其特定的粒度分布对每位客户而言都是独一无二的。

符合欧洲药典、美国药典-美国国家处方集和日本药典的要求

包装

- 15 kg纸板箱NL（铝箔/PE内衬袋）

有效期

3年

产地

荷兰Borculo

: 研磨乳糖
辅料功能: 载体
剂型: 剂型

典型产品数据

粒度分布（μm）

D10: 2.7
D50: 16

堆密度（g/L）

堆密度（g/L）: 400

振实密度 (g/L)

振实密度 (g/L): 680

卡尔指数（-）

卡尔指数（-）: > 25

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Effect of Loaded Dose on Delivered Dose in DPI 查看
Measurement of Lactose from DPI in Impactors 查看

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