Respitose® SV014 | Sieved lactose

製品情報

Respitose® SV014 は、優れた流動性と非常に大きな乳糖結晶を有する篩過吸入用乳糖グレードです。この最適な流動特性は、リザーバー装置への応用や、高用量吸入製剤において必要な流動性と含量均一性を維持するための機会を提供します。

また、本製品は、吸入時に乳糖が吸入器内の薬剤粒子を解砕し、薬剤を気道に推進させる「スイープナー」としても利用できます。Respitose® SV014は、オランダのVeghelにある専用設備で生産されています。Respitose® SV014 は、最適な乾燥粉末吸入製剤をより早く送達させるために、当社のソリューションのポートフォリオに加わるべき価値ある製品です。

最適な流動性

トマホーク型粒子と厳密に管理された粒子径分布の組み合わせにより、Respitose®SV014は優れた流動性を発揮します。

応用範囲の広さ

Respitose® SV014は、リザーバーデバイスで放出される製剤に適用することで、良好な流動性を持つ製剤を作ることができます。吸入用の高用量製剤では、Respitose® SV014は製剤の流動性の低下を補うことができます。また、Respitose® SV014の粗い粒子は、製剤中の薬物粒子の凝集を緩和し、気道への送達を容易にする役割を果たすことができます。DFEファーマの技術サポートにより、その他のアプリケーションも検討可能です。

Ph.Eur.、USP-NFおよびJPに準拠しています。

製品の種類: 篩過乳糖
添加剤の機能性: キャリア
剤形: 吸入

代表的な製品データ

粒度分布(μm)

D10: 245
D50: 365
D90: 545

嵩密度(g/L)

嵩密度(g/L): 720

タップ密度 (g/L)

タップ密度 (g/L): 810

Carrの流動性指数(-)

Carrの流動性指数(-): 12

ドキュメンテーション

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Shelf life statement lactose
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Particle size measurement of lactose for dry powder inhalers 表示
The influence of lactose particle size on DPI performance 表示
Designing inhalation grade lactose 表示
Exploring the design space for dry powder inhalers 表示
Effect of Lactose Processing on Dry Powder Inhaler Dispersion 表示
Different Types of Lactose Fines have an impact on different dry powder inhalers properties 表示
Effect of Loaded Dose on Delivered Dose in DPI 表示
Measurement of Lactose from DPI in Impactors 表示

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