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Anhydrous lactose

A solution of lactose is rapidly dried at high temperature to form anhydrous lactose which is then milled and sieved to the required particle size distribution. Anhydrous lactose offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Anhydrous lactose is also well suited for formulations containing moisture sensitive drugs, due to the absence of crystal water. It is the recommended form of lactose for dry granulation because its brittle nature allows re-compaction without loss of tabletability. DFE Pharma offers anhydrous lactose under the brandnames Lactopress® Anhydrous and SuperTab® AN. The specialty range products offer a selection of particle size distributions for improved flow or low dusting.
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Anhydrous

Excipients - Oral Solid Dose - Lactose - Anhydrous

Lactopress® Anhydrous

  • Anhydrous lactose grade
  • Highly compactable allowing re-compaction
  • Suitable for moisture sensitive drug
D10 D50 D90
Particle size 15 130 340
Sample size 500
Hausner ratio 1,42

Lactopress® Anhydrous Fine Powder

  • Anhydrous lactose grade
  • Finest Anhydrous grade
  • Suitable for Capsules
D10 D50 D90
Particle size 3 20 70
Sample size 500
Hausner ratio 1,6

Lactopress® Anhydrous Powder

  • Anhydrous lactose grade
  • Suitable for Capsules
  • Suitable for moisture sensitive drug
D10 D50 D90
Particle size 4 50 160
Sample size 500
Hausner ratio 1,55

SuperTab® 21AN

  • Anhydrous lactose grade
  • Highly compactable allowing re-compaction
  • Suitable for moisture sensitive drug
D10 D50 D90
Particle size 15 170 340
Sample size 500
Hausner ratio 1,25

SuperTab® 22AN

  • Anhydrous lactose grade
  • High compaction combined with enhanced flowability
  • Suitable for high dose actives
D10 D50 D90
Particle size 70 220 380
Sample size 500
Hausner ratio 1,17

SuperTab® 24AN

  • Anhydrous lactose grade
  • Optimal combination of powder flow, compaction
  • High dilution potential
D10 D50 D90
Particle size 35 120 260
Sample size 500
Hausner ratio 1,23